BioReactors
Bioreactor vessel is the widely used equipment in Pharmaceutical & Biotechnology Industry. Jalaram Pharma is widely known for its Bioreactor.
At JALARAM PHARMA, we work with our customers on projects of all sizes and scope.
As a premier Bioreactor vessel manufacturer, whether you need a Small pilot vessel or a Industrial scale large Bioreactor tank package, our knowledgeable team can provide you with a custom quote for your unique project.
Our portfolio contains a powerful range of engineering and manufacturing solutions, integrated to address the process and equipment needs which are critical to the cell-growth process. Our custom solutions meet industry best practice and local regulatory requirements.
In addition, we provide extensive aftermarket service and support, including spare parts, equipment upgrades, servicing and maintenance, as well as customer training.
Technical Specification
Type: Sterilization in Place (SIP) and Cleaning in Place (CIP)
Design Code: ASME BPE-2019
Temperature: 0 to 150 °C
pH: 2 to 14
DO2 : 0-100%
MOC: SS 316L/304 & ASTM grade
Automation Grade: Manual, Semi-Automatic & Fully Automatic
Surface Finish: Inner surface 420 grit mirror-finished Ra 0.25 to 0.5μm and External 120 to 180 grit hairline matt finish.
Capacity of Bioreactor Vessel
Bench top Bioreactor
Jacketed / Non jacketed
Capacity – 5 to 10 litres
Pilot Bioreactor
Jacketed / Non jacketed
Capacity – 15 to 50 litres
Industrial Bioreactor
Jacketed / Non jacketed
Capacity – 100 to 20,000 litres
Key Features
1. CIP ( Clean in Place )
2. SIP ( Sterilization in Place )
3. Customized & Tailor Made
4. Experienced Team & Support
Its design is based on:
Its design is based on:
- Standardized features, processes and components, including documentation and maintenance plan.
- Ergonomic design with an open and easy-to-access frame, integrated SIP and CIP and easily managed utilities.
- Customizable process control with spare signals for additional functions, expandable software and advanced Add-Ons.
Customized Agitator Blade Design
Single blade / Multi blade / Anchor blade / Perforated Blade / Single shaft / Twin Shaft
Our range of agitators and mixing blades is designed to meet the diverse needs of mixing applications across various industries. Featuring advanced design elements, including strategically placed baffle plates, our equipment ensures optimal mixing efficiency and performance.
By integrating our agitators and mixing blades into your processes, you can expect a noticeable improvement in process stability and product uniformity, leading to better overall production efficiency and product quality.
Jacket Heating
Our vessel is equipped with Jacket for uniform temperature environment during reactions.
- Steam Heating: Hot steam is circulated through the jacket to provide consistent and efficient heating. Ideal for rapid heat-up and maintaining high temperatures.
- Hot Water or Oil: For more precise temperature control, hot water or thermal oils can be used, circulating through the jacket at predetermined temperatures.
- Uniform Heating: Ensures even distribution of heat, preventing hot spots and ensuring consistent reaction conditions.
- Safety: External heating reduces the risk of direct contact between the heat source and the reactants, enhancing operational safety
Jacket Cooling
Our vessel is equipped with Jacket for uniform temperature environment during reactions.
- Cooling Water: Cold water is circulated through the jacket to remove excess heat from the reactor. This method is effective for moderate cooling requirements.
- Rapid Heat Removal: Efficiently dissipates heat, crucial for exothermic reactions where excess heat can alter or halt the desired chemical process.
- Temperature Stability: Helps maintain a constant temperature, crucial for reactions that are sensitive to temperature fluctuations.
- Prevents Overheating: Protects temperature-sensitive materials by quickly reducing temperatures when necessary, preserving the integrity of the product.
Salient Features. Peripherals
Customized Agitator / Mixing Blades ( Rushton, Marine, Anchor, etc )
Boiler feed pumps & Rotary vane pump
PH / DO / Temperature / Pressure / Vacuum sensors
Jacket Heat distribution system & Safety Valves
HMI Panel & Process Control monitoring
Automated Actuators & Steam Feed Valves
Oil Sampling valve
Steam Manifold
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Features
- Automated control of process parameters like temperature, aeration, pH.
- Top driven Agitator is provided through a single mechanical dry seal/double mechanical wet seal.
- Feed addition through a precise flow control meter for accuracy of feeding.
- Zero dead leg sampling valves and harvesting valves with in place steam sterilization system.
- Highly energy-efficient agitator drive, with a combination of specially designed Impellers like Rushton turbines.
- PLC-based panels are provided with a color touch screen HMI to provide the operator with monitoring and control of various parameters.
- Mobile App/web server is provided for data monitoring purposes.
- Alarms SMS alert on mobile is provided.
- Reserve data logging with SCADA software is also provided so that no important data of the batch is lost out.
- All wet parts are made of SS316/316L and non-wet parts are made of SS304.
Expertise
- Process engineering (functional analysis)
- Electrical and control system design, programming
- Piping manufacture and wiring
- Commissioning and after-sales service
- Qualification and Validation (cGMP, GAMP, CFR21 part 11)
- Design Qualification (DQ)
- Installation Qualification (IQ)
- Operational Qualification (OQ)
- Factory Acceptance Test (FAT)
- Site Acceptance Test (SAT)
- Performance Qualification (PQ)
Controls
- Automatic Temperature Control
- Automatic Exhaust Gas Pressure Monitoring & Control
- Automatic Agitation Control
- Automatic Back Pressure Monitoring
- Automatic pH Control
- Automatic Redox Monitoring & Control
- Automatic Vessel Sterilization Control
- Batch Recipe System
- Control Panel – Independent / Combined
- Mobile Application
- SMS Alert Facility
- Supervisory Control And Data Acquisition (SCADA)
Why Choose Us ?
Lab Tested Material with TC reports
We provide products with TC reports for better transparency and quality.
Quality assurance with precision
We make the products with highest accuracy and precision.
Experienced professionals
We have experience professionals in all domains from Metal to Plastic
Highest quality fabrication
All our working professionals are Skilled and experienced
Client Testimonials
Precise Welding - TIG / MIG ( Technology )
We provide RT (Radiographic) / DP (Dye Penetrant) test reports of Welded Joints of our Reactor vessel .
Our welding is performed by experienced professionals, supervised by highly skilled experts to ensure top quality.